Simply eating less and exercising more is not enough to help most people remove excess body fat and keep it off. Scientists have identified specific biological mechanisms that cause people to gain weight, no matter how little they eat! The body can accumulate excess fat several different ways:

• Leptin Resistance- Leptin is the hormone that tells the brain it is full, but as we age our cells become leptin-resistant and this normal function is impaired.
• Extra large fat cells- an enlargement of these cells occurs during weight gain and they secrete less adiponectin, a hormone that supports insulin sensitivity and cardiovascular health.
• Excess of fat converting enzyme- an enzyme called glycerol-3-phosphate dehydrogenase helps convert glucose into triglycerides that increase fat cell size.

A comprehensive program is necessary to target the many factors that contribute to excess body fat. A new supplement by Life Extension called Integra-Lean Irvingia addresses these underlying factors. The key ingredient in this product, Irvingia gabonensis, is a native plant to Central and West Africa. The traditional diet of this region consists of meals rich in Irvingia gabonensis and these particular population groups have been described as physically leaner and much less prone to Type 2 diabetes and its related complications. Integra-Lean Irvingia can maintain a healthy body weight by:

• Lowering the level of C-reactive protein (CRP; causes leptin resistance) in fat cells thereby reversing leptin resistance, which enables the breakdown of fat cells and turns off the brain’s chronic hunger messages. In a clinical study, researchers found that weight loss at 8 and 10-weeks was greater than weight loss at 4-weeks while taking this supplement. They believe this occurs because over time sensitivity to leptin receptors is restored enabling more effective signaling in the brain’s appetite control center.
• Increasing adiponectin secretion leading to shrinkage of fat cells.
• Suppressing the fat converting enzyme which reduces the amount of sugar converted to fat in the body.
• Irvingia reduces the amount of carbs that will be absorbed as sugar by inhibiting the amylase digestive enzyme.

Several studies have demonstrated the weight loss properties of Irvingia. In the largest placebo controlled human study, those taking Irvingia lost 28 pounds over a 10-week period compared to only up to 3 pounds in the placebo group (the study participants did not alter their diet). Based on striking human data, a dose of 150 mg of Integra-Lean Irvingia taken twice a day achieved unprecedented clinical results. This supplement should be taken in conjunction with a healthy diet and regular exercise program for optimal results. Life Extension believes so strongly in this product, they are offering a money-back guarantee if you are not satisfied with your results after 10 weeks.

The suggested use of Integra-Lean Irvingia is 1 cap twice a day with or without food. There are 150 mg of Irvingia gabonensis extract in each cap and each bottle contains 60 caps at $56.00.

To order or for additional information, call Jeff at (919) 781-9994 or jeff@totalhealthnutritioncenter.com

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.